Abstract: Objective: To observe the clinical efficacy of traditional Chinese medicine Traumatology Intramuscular Patch on elderly knee osteoarthritis. Methods: 99 patients with knee osteoarthritis (KOA) who were admitted to our hospital from February 2021 to March 2022 were selected as the study subjects and randomly divided into kinesio taping (KT) group, KT+plaster group, and trauma KT group. The KT group was treated with intramuscular patches (KT) alone; The KT+plaster group was treated with intramuscular plaster combined with Shangke Pain Relieving Cream; The KT group in the Department of Traumatology was treated with traditional Chinese medicine Traumatology intramuscular plaster. Three groups were subjected to visual analog scale (VAS), proprioception assessment (active angle reproduction (AAR), and threshold to detect passive motion (TDPM) before and after treatment, as well as Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Muscle bone ultrasound indicators (maximum depth of fluid accumulation, Szkudlarek grading of synovial membrane) and laboratory indicators detection [tumor necrosis factor]-α (TNF-α)、 Matrix metalloproteinase 9 (MMP-9), osteoprotegerin (OPG), chemokine 12 in synovial fluid (CXCL12). Results: ① Comparison of VAS score, proprioception evaluation, and WOMAC scale: The KT group in the Department of Traumatology had lower VAS score, proprioception evaluation (AAR, TDPM) than the KT group (P<0.05), and had no statistical significance compared to the KT+plaster group (P>0.05); In the WOMAC scale, the KT group in the Department of Traumatology scored lower than the other two groups in terms of "pain" and "daily activities", and only lower than the KT group in terms of "stiffness", with no difference compared to the KT+plaster group Comparison of muscle bone ultrasound indicators: The KT group in the Department of Traumatology had lower Szkudlarek grading in maximum fluid accumulation depth and synovial membrane compared to the other two groups (P<0.05) Comparison of indicators in the laboratory: KT group in the field of traumatology in TNF-α. The levels of MMP-9 and CXCL12 were lower than those of the other two groups (P<0.05), while in the OPG trauma KT group, they were only higher than those in the KT group, and there was no statistically significant difference compared to the KT+plaster group (P>0.05). Conclusion: The traditional Chinese medicine Traumatology Intramuscular Patch can effectively inhibit the symptoms of pain, swelling, and limited movement in elderly KOA patients, improve synovial hyperplasia and multiple laboratory indicators, and its effect is better than using Intramuscular Effect Patches alone or the combination of muscle patches and Traumatology Pain Relief Cream.

Key words: Traditional Chinese Medicine Traumatology Intramuscular Patch, aged people, kinesio taping, muscle bone ultrasound, Traumatology Pain Relief Cream, Intramuscular Effect Patch