Abstract: PurposesThe purpose of the research is to explore the effect of slim exercise prescription on overweight college students' WHR, plasma visfatin and plasma adiponectin. Methods9 male and 13 female overweight students are used as subjects. Individual slim exercise prescriptions are worked out after the test of body shape, body function and sports ability. The exercise intensity is determied aroud 60-70 of the maxmum sports ability and the RPE is set between 13-15. Each exercise lasts for 60 minutes, 5 times per week RPE with the exercise intervention for 8 weeks. The relevant indexes are measure before and after exercise. Results8 weeks of slim exercise prescription results in a significant decrease (P＜0.01)in both male and female subjects' BMI, body fat rate (FAT%), waist and hip circumference ratio (WHR). Plasma visfatin and adiponectin levels indicate a significant difference between the male and the female compared with indexes befeore exercise ((P<0.01). There is an obvious correlation in males between visfatin, BMI and obesity index. Plasma visfatin levels in females are significantly associated with BMI, body weight and body fat. Plasma adiponectin level in males and females both have significant negative correlation with BMI, obesity index and waist-to-hip ratio. ConclusionsSlim exercise prescription for 8 weeks effectively improves the situation of the overweight and obese students by significantly decreasing plasma visfatin and increasing plasma adiponectin, for plasma visfatin and adiponectin leaves can be used as the indirect indexes to reflect obese people's metabolism.

Key words: exercise prescription, university students, overweight and obesity, WHR, visfatin, adiponectin