关键词: 跑节省化, 有氧运动能力, 尿游离miRNA, 可训练性, 运动员选材

Abstract: Objective: miRNAs affect the trainability of athletic ability by regulating the essential processes of exercise adaption. The expression profile of Urine cell-free miRNAs (UCF-miRNAs) associates with the pattern of miRNA in tissue. The research is to build the model of UCF-miRNA expressing pattern reflecting the trainability of aerobic athletic ability. Method: 91 healthy male freshmen without any experience of aerobic training are engaged in a 17-week aerobic training with the running economy (RE/R-RE) before and after the training were measured, and then the subjects are grouped as High Response group(HR group) and Common Response group(CR group), depending on the result of the K-means clustering of growth ratio of R-RE. The characters of UCF-miRNAs’ Differential Expression Profil were extracted and analyzed. Result: 12 UCF-miRNAs are closely related to exercise adoption and their expressing patterns are extracted, validated and confirmed to constitute the differential expression profile of HR group which is characteristic of higher growth ratio of R-RE with its Differential Expression Profile coincides with the positive characters of aerobic athletic ability. Conclusion: UCF-miRNAs’ Differential Expression Profile is closely related to the trainability of aerobic athletic ability, which can be used as a method to forecast the potential of aerobic athletic ability and to value the effect of training early and accurately.

Key words: Running Economy, Aerobic Athletic Ability, UCF-miRNA, Trainability, Selection